In the present study, 2-amino-4-methyl-5-(pyridin-2-ylcarbamoyl)thiophene-3-ethylcarboxylate (2) has been achieved using Gewald’s methodology between 3-oxo-N-(pyridin-2-yl)butanamide (1), ethyl 2-cyanoacetate and elemental sulfur in refluxing ethyl alcohol containing a catalytic amount of morpholine. This 2-aminothiophene derivative was served as key synthon for the synthesis of new thiazolidin-4-one, chromen-2-imine and pyrrol-2-one derivatives via its reactions with the convenient chemical reagents. The mechanistic aspects for the achievement of the new thiophene derivatives were also discussed
(2019). Convenient synthesis of some new thiazolidin-4-one, chromen-2-imine and pyrrol-2-one derivatives containing thiophene moiety. Mansoura Journal of Chemistry, 46(4), 7-11. doi: 10.21608/mjcc.2019.413044
MLA
. "Convenient synthesis of some new thiazolidin-4-one, chromen-2-imine and pyrrol-2-one derivatives containing thiophene moiety", Mansoura Journal of Chemistry, 46, 4, 2019, 7-11. doi: 10.21608/mjcc.2019.413044
HARVARD
(2019). 'Convenient synthesis of some new thiazolidin-4-one, chromen-2-imine and pyrrol-2-one derivatives containing thiophene moiety', Mansoura Journal of Chemistry, 46(4), pp. 7-11. doi: 10.21608/mjcc.2019.413044
VANCOUVER
Convenient synthesis of some new thiazolidin-4-one, chromen-2-imine and pyrrol-2-one derivatives containing thiophene moiety. Mansoura Journal of Chemistry, 2019; 46(4): 7-11. doi: 10.21608/mjcc.2019.413044
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